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Updated: Dec 15, 2025

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test
Published on: April 9, 2012
A pilot study to evaluate urine LAM assay for diagnosis of pulmonary tuberculosis among non-HIV patients
Akshita Gupta1, Ajay Kumar2, Asem Ali Ashraf1
1Junior Resident, Department of Microbiology, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Abstract:
There is a great need to improve diagnostic tools for tuberculosis where the majority are without HIV co-infection in resource-poor settings and high-burden areas such as India. The urine LAM assay has not hitherto been studied and may have a role to play. Our study found that, as a stand-alone diagnostic tool, the assay was suboptimal when compared to Xpert MTB/Rif. However, a combination of LAM assay along with sputum microscopy may be useful in settings where molecular testing is unavailable.
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