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Updated: Dec 15, 2025

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
Published on: February 7, 2017
Recent advances in higher order rotaxane architectures
He-Ye Zhou1, Qian-Shou Zong2, Ying Han3
1Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. cchen@iccas.ac.cn hanying463@iccas.ac.cn and University of Chinese Academy of Sciences, Beijing 100049, China.
Abstract:
Despite dramatic advances in the template-directed synthesis of archetypal [2]rotaxanes, higher order rotaxanes with multiple molecular components (rings or dumbbells) are relatively daunting subjects owing to their synthetic challenges. With unique interlocked architectures, higher order rotaxanes have found applications in artificial molecular machines. In this feature article, we will focus on the recent advances in higher order rotaxanes with well-defined structures. Different types of rotaxane architectures will be described, and their synthetic approaches will be highlighted. Moreover, the stimuli-responsive molecular motion with increasing complexity in these diverse architectures will also be discussed.
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