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Diagnostic Challenges in Chondroblastic Maxillary Osteosarcoma: A Case Report.
Mohannad K Rajab1, Baraa I Awad2, Hadi Afandi Al-Hakami3
1Otolaryngology-Head and Neck Surgery, Ministry of Health, Makkah, SAU.
Cureus
|July 10, 2020
Summary
Diagnosing craniofacial osteosarcoma is difficult, often leading to delayed treatment. This case highlights the need for high suspicion and prompt surgical intervention for better outcomes in rare chondroblastic osteosarcoma.
Area of Science:
- Oncology
- Maxillofacial Surgery
- Pathology
Background:
- Craniofacial osteosarcomas are rare bone cancers.
- Delayed diagnosis is common due to subtle initial symptoms.
- Chondroblastic osteosarcoma is a high-grade subtype.
Observation:
- A 21-year-old woman presented with a year-long swelling on her maxillary alveolar ridge.
- Histopathology confirmed high-grade chondroblastic osteosarcoma.
- The tumor was located in the craniofacial region.
Findings:
- Neoadjuvant chemotherapy was administered preoperatively.
- A left inferior maxillectomy was performed.
- Reconstruction was achieved using an obturator prosthesis.
Implications:
- This case underscores diagnostic challenges in craniofacial osteosarcoma.
- Early detection and surgical resection with wide margins are crucial.
- Management protocols require careful consideration for rare presentations.

