Related Experiment Video

Updated: Dec 15, 2025

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
05:31

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

1.1K

Potential Protein Biomarkers for Preeclampsia

Andong He1, Yixuan Zhou1, Yiling Wei1

  • 1Obstetrics and Gynecology, The First Affiliated Hospital of Jinan University, Guangzhou, CHN.

Cureus
|July 10, 2020
PubMed

Insights

Early prediction of preeclampsia (PE) is crucial due to unclear causes and lack of specific treatments. Proteomics identifies potential protein biomarkers for PE prediction and understanding disease mechanisms.

Area of Science:

  • Biochemistry
  • Medical Science
  • Genomics

Background:

  • Preeclampsia (PE) etiology remains unclear, necessitating improved prediction and prevention strategies.
  • Current treatments for PE are limited, highlighting the need for early diagnostic tools.
  • Proteomics offers a powerful approach to discover biomarkers associated with PE.

Purpose of the Study:

  • To review the application of proteomics in preeclampsia research.
  • To identify potential protein biomarkers for PE prediction.
  • To enhance understanding of PE's pathological mechanisms.

Main Methods:

  • Literature review of proteomics studies in preeclampsia.
  • Analysis of identified protein biomarkers.
  • Synthesis of findings to guide future research.

Main Results:

  • Proteomics has identified numerous potential protein biomarkers for PE.
  • These biomarkers aid in predicting PE onset and understanding its pathology.
  • The review consolidates current knowledge on proteomics in PE.

Conclusions:

  • Proteomics is instrumental in advancing preeclampsia biomarker discovery.
  • Further research is needed to validate these biomarkers for clinical application.
  • Understanding protein changes can lead to better PE management.

Keywords:
biomarkerspredictionpreeclampsiaproteinproteomics

More Related Videos

The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo12:17

The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo

Published on: August 2, 2017

11.0K
Hydrogel Nanoparticle Harvesting of Plasma or Urine for Detecting Low Abundance Proteins10:05

Hydrogel Nanoparticle Harvesting of Plasma or Urine for Detecting Low Abundance Proteins

Published on: August 7, 2014

14.2K

Related Concept Videos

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
421
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
669