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A bibliometric analysis and review of recent researches on TRPM7
Shiqi Zhang1, Dongyi Zhao1, Wanying Jia1
1Department of Pharmaceutical Toxicology, School of Pharmaceutical Science, China Medical University , Shenyang, China.
Abstract:
The transient receptor potential melastatin-subfamily member 7 (TRPM7) is a ubiquitously expressed protein that contains both an ion channel and an active kinase. TRPM7 has involved in a variety of cellular functions and critically participates in various diseases mainly including cancer and neurodegenerative disorders. However, the theme trends and knowledge structures for TRPM7 have not yet been studied bibliometrically. The main purposes of this research are to compare the scientific production in the research field of TRPM7 among countries and to evaluate the publication trend between 2004 and 2019. All publications were extracted from the Web of Science Core Collection (WoSCC) database from 2004 to 2019. Microsoft Excel 2018, Prism 6, and CiteSpace V were applied to analyze the scientific research outputs including journals, countries, territories, institutions, authors, and research hotspots. In this report, a total of 860 publications related to TRPM7 were analyzed. Biophysical Journal ranked top for publishing 31 papers. The United States of America had the largest number of publications (320) with a high citation frequency (11,298) and H-index (58). Chubanov V (38 publications) and Gudermann T (38 citations), who from Ludwig Maximilian University of Munich, were the most productive authors and had the greatest co-citation counts. Our study also combined the bibliometric study with a systematic review on TRPM7, highlighting the four research frontiers of TRPM7. This is the first study that demonstrated the trends and future development in TRPM7 publications, providing a clear and intuitive profile for the contributions in this field.
Insights
This bibliometric study analyzes transient receptor potential melastatin-subfamily member 7 (TRPM7) research from 2004-2019. The USA leads in TRPM7 publications, with key authors and institutions identified, revealing emerging research frontiers.
Area of Science:
- Biomedical Sciences
- Molecular Biology
- Cellular Physiology
Background:
- Transient receptor potential melastatin-subfamily member 7 (TRPM7) is a dual-function protein with ion channel and kinase activity.
- TRPM7 plays a crucial role in cellular functions and is implicated in diseases like cancer and neurodegenerative disorders.
- Bibliometric analysis of TRPM7 research trends and knowledge structure was previously lacking.
Purpose of the Study:
- To compare international scientific output on TRPM7.
- To evaluate publication trends in TRPM7 research from 2004 to 2019.
- To identify key research hotspots and frontiers in the TRPM7 field.
Main Methods:
- Bibliometric analysis of 860 publications from the Web of Science Core Collection (2004-2019).
- Utilized software including Microsoft Excel, Prism 6, and CiteSpace V for data analysis.
- Combined bibliometric data with a systematic review to identify research frontiers.
Main Results:
- Biophysical Journal published the most papers (31).
- The United States led in publications (320), citations (11,298), and H-index (58).
- Authors Chubanov V and Gudermann T were highly productive and cited.
Conclusions:
- This study provides the first bibliometric overview of TRPM7 research trends and contributions.
- Identified four key research frontiers in TRPM7.
- Offers insights into the field's development and future directions.
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