Related Experiment Video
Updated: Dec 15, 2025

Author Spotlight: Development of Simplified CRISPR-Based Tests for Rapid Detection of Infectious Diseases
Published on: August 16, 2024
Next-generation pathogen diagnosis with CRISPR/Cas-based detection methods
Xinjie Wang1, Xiaoyun Shang2, Xingxu Huang3
1Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, People's Republic of China.
Abstract:
Ideal methods for detecting pathogens should be sensitive, specific, rapid, cost-effective and instrument-free. Conventional nucleic acid pathogen detection strategies, mostly PCR-based techniques, have various limitations, such as expensive equipment, reagents and skilled performance. Recently, CRISPR/Cas-based methods have burst onto the scene, with the potential to power the pathogen detection field. Here we introduce these unique methods and discuss its hurdles and promises.
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