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Bacteriophage Effectiveness for Biocontrol of Foodborne Pathogens Evaluated via High-Throughput Settings
Published on: August 19, 2021
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Phage Biocontrol Applications in Food Production and Processing
Amit Vikram1, Joelle Woolston1, Alexander Sulakvelidze1
1Intralytix, Inc., Columbia, Maryland 21046, USA.
Current Issues in Molecular Biology
|July 10, 2020
Summary
Bacteriophages (phages) show promise for food safety applications, particularly post-harvest. This review covers their use in biocontrol, available products, and current challenges.
Area of Science:
- Microbiology
- Food Science
- Biotechnology
Background:
- Bacteriophages (phages) are ubiquitous microorganisms with growing interest in practical applications.
- Phage biocontrol is gaining momentum for food safety, with increasing regulatory approvals.
- Applications include pre-harvest, post-harvest, and food contact surface decontamination.
Purpose of the Study:
- This review focuses on the post-harvest application of bacteriophage biocontrol.
- It also briefly describes commercially available phage preparations.
- The review discusses challenges and future prospects of phage biocontrol in food safety.
Main Methods:
- Literature review of bacteriophage applications in food safety.
- Focus on post-harvest interventions.
- Analysis of commercially available phage products and regulatory landscape.
Main Results:
- Post-harvest application of phages is the most common current use of phage biocontrol.
- Several commercial phage preparations are available for food safety.
- Regulatory approvals are increasing, indicating growing acceptance.
Conclusions:
- Bacteriophage biocontrol, especially post-harvest, is a promising approach for enhancing food safety.
- Commercialization and regulatory progress are evident.
- Overcoming existing challenges is key to wider adoption.
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