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Summary

This summary is machine-generated.

Optimizing intraocular lens (IOL) power calculation formulas with swept-source optical coherence tomography (SS-OCT) biometry improves accuracy. The Olsen, Barrett, Kane, and EVO 2.0 formulas demonstrated the best refractive prediction outcomes.

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Area of Science:

Ophthalmology
Biomedical Optics
Surgical Technology

Background:

Accurate intraocular lens (IOL) power calculation is crucial for achieving desired refractive outcomes after cataract surgery.
Swept-source optical coherence tomography (SS-OCT) provides high-resolution biometry measurements for IOL power calculations.
Various IOL power calculation formulas exist, with varying accuracy depending on the biometry data used.

Purpose of the Study:

To evaluate the accuracy of modern IOL power calculation formulas using SS-OCT biometry.
To compare the performance of artificial intelligence-based and standard Gaussian optics-based formulas.
To assess the impact of optimized constants for SS-OCT biometry on formula accuracy.

Main Methods:

Retrospective analysis of 410 eyes undergoing cataract surgery with SS-OCT biometry (IOLMaster 700).
Comparison of newly released AI-based formulas (Hill-Radial Basis Function 2.0, Kane, PEARL-DGS) against standard formulas.
Evaluation of refractive prediction accuracy by comparing predicted spherical equivalent with actual postoperative refraction.

Main Results:

Optimized SS-OCT biometry constants significantly reduced median absolute error (MedAE) for several standard formulas.
The Olsen and Kane formulas exhibited the lowest MedAEs (0.283 D and 0.286 D, respectively) after constant optimization.
Formulas like Olsen, Barrett, Kane, and EVO 2.0 showed a higher proportion of eyes within ±0.25 D of predicted refraction.

Conclusions:

Constant optimization for SS-OCT biometry enhances the performance of IOL power calculation formulas.
The Barrett, EVO 2.0, Kane, and Olsen formulas provide the most accurate prediction of postoperative refraction.
These findings support the use of advanced formulas with SS-OCT biometry for improved refractive outcomes in cataract surgery.