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Published on: February 6, 2021
Endogenous Endophthalmitis Caused by Isolated Listeria Monocytogenes Infection
Kevin Smeets1, Rita Van Ginderdeuren1,2, Joachim Van Calster1
1Department of Ophthalmology, University Hospitals Leuven, Leuven, Belgium.
Abstract:
Purpose: The purpose of this report is to present an extremely rare case of endogenous Listeria monocytogenes endophthalmitis.Methods: A 72-year-old woman was diagnosed with endogenous endophthalmitis. Listeria monocytogenes was identified by culture of aqueous humor. Multiple investigations could not reveal any source of infection. An overview of other published cases is presented and a standardized treatment protocol is suggested.Results: Treatment consisted of topical therapy with antibiotics, corticosteroids, cycloplegics, and intraocular pressure-lowering agents, four intravitreal injections of vancomycin, an anterior chamber washout, intravenous amoxicillin, and eventually a pars plana vitrectomy. The inflammation subsided and the patient was discharged with a best-corrected visual acuity of 20/40.Conclusion: Our study emphasizes the importance of adequate microbiological testing and initiating appropriate treatment early in the management of endogenous endophthalmitis.
Insights
This report details a rare case of endogenous Listeria monocytogenes endophthalmitis. Prompt diagnosis and comprehensive treatment led to visual recovery.
Area of Science:
- Ophthalmology
- Infectious Diseases
Background:
- Endogenous endophthalmitis is a severe intraocular infection.
- Listeria monocytogenes is an uncommon cause of endophthalmitis.
Observation:
- A 72-year-old woman presented with endogenous endophthalmitis.
- Listeria monocytogenes was confirmed via aqueous humor culture.
- No clear source of infection was identified.
Findings:
- Treatment involved topical and systemic antibiotics, corticosteroids, and surgical interventions.
- The patient received intravitreal vancomycin and an anterior chamber washout.
- Pars plana vitrectomy was performed, resulting in inflammation subsidence.
Implications:
- This case highlights the importance of thorough microbiological investigation.
- Early and appropriate treatment is crucial for managing endogenous endophthalmitis.
- A standardized treatment protocol may improve patient outcomes.
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