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Migrating pseudolipoma of Glisson's capsule
Megan Elizabeth Kiolbasa1, Nanda Deepa Thimmappa2, James Derek Stensby2
1Kansas City University of Medicine and Biosciences, Kansas City, MO, USA.
Clinical Imaging
|July 10, 2020
Summary
This case report details a rare liver lesion, pseudolipoma of Glisson
Area of Science:
- Hepatobiliary Medicine
- Radiology
- Surgical Pathology
Background:
- Pseudolipomas of Glisson's capsule are uncommon benign liver lesions.
- These lesions are characterized by degenerating fat, potentially originating from detached epiploic appendages.
- Computed Tomographic (CT) imaging reveals them as well-circumscribed, hypoattenuating subcapsular masses.
Observation:
- This case report presents three consecutive CT scans of a single patient.
- The scans document a pseudolipoma of Glisson's capsule migrating within the liver.
- Migration occurred over a 4.5-month period to a subcapsular hepatic location.
Findings:
- The pseudolipoma exhibited well-circumscribed and hypoattenuating characteristics on CT.
- This is the first documented instance of pseudolipoma migration over time.
- The observed migration supports the epiploic appendage hypothesis.
Implications:
- This finding supports the theory of migrating epiploic appendages forming Glisson's capsule pseudolipomas.
- Understanding lesion migration aids in accurate diagnosis and differential diagnosis of liver masses.
- Further research into the dynamics of these rare lesions is warranted.

