Related Experiment Video

Updated: Dec 15, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

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The GABAB Receptor-Structure, Ligand Binding and Drug Development.

Linn Samira Mari Evenseth1, Mari Gabrielsen1, Ingebrigt Sylte1

  • 1Molecular Pharmacology and Toxicology, Department of Medical Biology, Faculty of Health Sciences, UiT The Arctic University of Norway, NO-9037 Tromsø, Norway.

Molecules (Basel, Switzerland)
|July 11, 2020
PubMed
Summary

The gamma-aminobutyric acid type B receptor (GABAB-R) is crucial for central nervous system inhibition. This review explores its structure, function, and potential for developing new drugs targeting various disorders.

Keywords:
GABAB receptorsallosteric binding sitebaclofendrug developmentorthosteric binding sitestructural mechanisms

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