Automatic Midline Identification in Transverse 2-D Ultrasound Images of the Spine

Effective epidural needle placement and injection involves accurate identification of the midline of the spine. Ultrasound, as a safe pre-procedural imaging modality, is suitable for epidural guidance because it offers adequate visibility of the vertebral anatomy. However, image interpretation remains a key challenge, especially for novices. A deep neural network is proposed to automatically classify the transverse ultrasound images of the vertebrae and identify the midline. To distinguish midline images from off-center frames, the proposed network detects the left-right symmetric anatomic landmarks. To assess the feasibility of the proposed method for midline detection, a data set of ultrasound images was collected from 20 volunteers, whose body mass indices were less than 30. The data were split into two segments, for training and test. The performance of the proposed method was further evaluated using fourfold cross validation. Moreover, it was compared against a state-of-the-art deep neural network. Compared with the gold standard provided by an expert sonographer, the proposed trained network correctly classified 88% of the transverse planes from unseen test patients. This capability supports the first step of guiding the placement of an epidural needle.