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Updated: Dec 15, 2025

Generation of Escape Variants of Neutralizing Influenza Virus Monoclonal Antibodies
Published on: August 29, 2017
Broadly Neutralizing Antibodies to Highly Antigenically Variable Viruses as Templates for Vaccine Design
Matthias G Pauthner1, Lars Hangartner2
1The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.
Abstract:
Development of vaccines to highly variable viruses such as Human Immunodeficiency Virus and influenza A viruses faces multiple challenges. In this article, these challenges are described and reverse vaccinology approaches to generate universal vaccines against both pathogens are laid out and compared.
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