Read-across: Principle, case study and its potential regulatory application in China

Area of Science:

• Toxicology
• Chemical Risk Assessment
• Regulatory Science

Background:

• Read-across is an internationally recognized alternative testing strategy for chemical safety assessment.
• Its regulatory application in China's chemical management system is currently limited but progressing.
• A dedicated workshop convened experts to address the broader adoption of read-across in China.

Purpose of the Study:

• To discuss the principles and case studies of read-across.
• To explore the potential for wider regulatory application of read-across in China.
• To identify barriers and propose strategies for facilitating read-across acceptance.

Main Methods:

• A workshop format involving global experts from regulatory bodies, academia, and industry.
• Scientific presentations on read-across applications and regulatory acceptance.
• Constructive discussions and brainstorming sessions.

Main Results:

• Increased awareness regarding the global use of read-across and its challenges.
• Identification of specific barriers hindering regulatory acceptance in China.
• Development of practical strategies to promote the use of read-across approaches.

Conclusions:

• Read-across holds significant potential to support chemical risk assessment in China.
• Addressing identified barriers is crucial for enhancing regulatory acceptance.
• Collaborative efforts are needed to facilitate the broader implementation of read-across.