Related Experiment Video For HPV
Updated: Dec 15, 2025
RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
HPV-related carcinoma of the oropharynx: challenges on small biopsy specimens
Doreen Palsgrove1, Justin A Bishop1
1Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas.
Abstract:
Human papillomavirus (HPV)-related oropharyngeal carcinoma can morphologically mimic many processes from benign to malignant and lead pathologists to incorrectly diagnose them and/or use inappropriate diagnostic terminology. Recognition of HPV-related oropharyngeal carcinoma and its variants is critical for appropriate prognostic and therapeutic considerations in small biopsy material. Various pitfalls in diagnosing these tumors on limited biopsies are discussed herein.
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