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Catalytically-active inclusion bodies for biotechnology-general concepts, optimization, and application.

Vera D Jäger1,2,3, Robin Lamm2,4, Kira Küsters5,6

  • 1Institut für Molekulare Enzymtechnologie, Heinrich-Heine-Universität Düsseldorf, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.

Applied Microbiology and Biotechnology
|July 12, 2020
PubMed
Summary

Catalytically active inclusion bodies (CatIBs) are engineered protein aggregates with inherent enzymatic activity. This review explores their production, processing, and applications as novel bionanomaterials in biotechnology.

Keywords:
BiocatalysisCatalytically active inclusion bodiesEnzyme immobilizationProtein co-localizationProtein engineeringSynthetic biologySynthetic reaction cascadesUpstream and downstream processing

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