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Updated: Jul 18, 2026

Collecting And Measuring Wound Exudate Biochemical Mediators In Surgical Wounds
Published on: October 20, 2012
A topical naltrexone formulation for surgical wound healing: A case report
Jack Dunn1, Yi Liu2, Fabiana Banov3
1Jasper Drug Store, Jasper, Georgia, USA.
Background:
In current guidelines, there is no specific therapeutic recommendation for promoting surgical wound healing. Proper postsurgical wound care regimen can speed up wound healing and prevent abnormal scarring.
Aims:
The purpose of this case study was to evaluate the effectiveness of a compounded topical formulation containing naltrexone in managing surgical wound in a patient after Mohs micrographic surgery (MMS).
Patients/Methods:
A patient started to apply the topical naltrexone formulation two days after the MMS on his hand. Images of the wound and a Patient Scar Assessment Questionnaire (PSAQ) were used to evaluate the clinical outcomes.
Results:
The wound completely healed, and the hand function was fully recovered following application of the formulation for 2 weeks. No abnormal scarring was formed, and the scar was only slightly noticeable after 2 months.
Conclusion:
This case study demonstrated the effectiveness of the topical naltrexone formulation in surgical wound management.
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