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Women with chronic kidney disease undergoing transcatheter aortic valve replacement: Caveat emptor

Puja B Parikh1, John P Reilly1

  • 1Division of Cardiovascular Medicine, Department of Medicine, State University of New York at Stony Brook, Stony Brook, New York, USA.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|July 12, 2020
PubMed

Insights

Over 60% of women undergoing transcatheter aortic valve replacement (TAVR) have chronic kidney disease (CKD). This condition significantly increases adverse events and mortality risk in these patients.

Area of Science:

  • Cardiology
  • Nephrology
  • Geriatric Medicine

Background:

  • Transcatheter aortic valve replacement (TAVR) is a common procedure for aortic stenosis.
  • A significant proportion of women undergoing TAVR present with coexisting chronic kidney disease (CKD).

Discussion:

  • Chronic kidney disease (CKD) in women undergoing TAVR is linked to substantially higher rates of adverse events.
  • A twofold increased rate of risk-adjusted mortality at one year was observed in women with CKD post-TAVR.

Key Insights:

  • CKD represents a critical risk factor for adverse outcomes in women undergoing TAVR.
  • Risk stratification models for TAVR in women need to incorporate CKD status.

Outlook:

  • Further research is warranted to explore strategies for optimizing outcomes in high-risk women with CKD undergoing TAVR.
  • Investigating targeted interventions for women with CKD undergoing TAVR may improve long-term survival and reduce complications.

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