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Published on: August 17, 2011
Bibliometric analysis of calcium channel research (2010-2019)
Jingjing Shi1, Huan Wang1, Shuqing Shi2
1Guanganmen Hospital, China Academy of Chinese Medical Sciences , Beijing, China.
Insights
This bibliometric analysis reveals key trends in calcium channel research from 2010-2019. It identifies leading institutions and countries, highlighting research hotspots and emerging frontiers in this vital area of study.
Area of Science:
- Biomedical Sciences
- Pharmacology
- Molecular Biology
Background:
- Calcium channels are crucial in various pathologies affecting cardiac, neurological, metabolic, and respiratory systems.
- Decades of research exist, but a bibliometric analysis of trends and hotspots is lacking.
Purpose of the Study:
- To conduct a bibliometric analysis of calcium channel research from 2010-2019.
- To identify research hotspots and emerging frontier trends in the field.
Main Methods:
- Bibliometric analysis of 26,664 publications from the Web of Science Core Collection (2010-2019).
- Utilized CiteSpace 5.6 R5 for analyzing countries, institutions, authors, and research areas.
Main Results:
- The United States and the University of California led in publications.
- Key research hotspots included calcium channel regulation, blockers, and ryanodine receptors.
- Emerging frontiers involved calcium channel effects on cell proliferation, gene mutation, neuropathic pain, and signaling pathways.
Conclusions:
- This study provides the first visualization and analysis of hotspots and emerging trends in calcium channel research.
- Identified leading contributors and key research areas, offering insights for future investigations.
Abstract:
Calcium channels are involved in pathologies across all the major therapeutic areas involving the cardiac, neurological, metabolic, and respiratory systems. Although calcium channels have been the hotspot of multidisciplinary research for decades, the hotspots and frontier trends of calcium channel research have not been comprehensively analyzed by bibliometrics. Here, we collected scientific publications on calcium channel research in the past decade to explore the hotspots and frontier directions of calcium channel research by bibliometric analysis. Publications were retrieved from the Web of Science Core Collection (WOSCC) database from 2010 to 2019. Citespace5.6 R5 was used to perform bibliometric analysis on the countries, institutions, authors, and related research areas. In total, 26,664 articles were analyzed. The United States and the University of California are the most productive country and institution for calcium channel research. The most productive researchers were Lang, Florian, Zamponi, Gerald W, and Jan, Chung-Ren. PLoS One had the most significant number of publications (986). Research hotspots can be summarized as the regulation mechanism of calcium channels, calcium channel blockers, and ryanodine receptor. The research frontiers were the effect of calcium channel on cell proliferation, gene mutation, calcium channels in neuropathic pain, and calcium-signaling pathway. This is the first report to visualize and analyze hotspots and emerging trends in calcium channel research.
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