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Clinical observations on nail changes in psoriasis.

S N Tham1, J J Lim, S H Tay

  • 1Middle Road Hospital, Singapore.

Annals of the Academy of Medicine, Singapore
|October 1, 1988
PubMed
Summary
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Nail changes are prevalent in 78% of psoriasis patients, with pitting and onycholysis being most common. Severity, duration, age, and joint involvement correlate with increased nail abnormalities.

Area of Science:

  • Dermatology
  • Rheumatology
  • Clinical Medicine

Background:

  • Psoriasis is a chronic inflammatory skin condition.
  • Nail involvement is a common manifestation of psoriasis, impacting patient quality of life.
  • Understanding the prevalence and patterns of nail changes is crucial for comprehensive patient management.

Purpose of the Study:

  • To investigate the prevalence and types of nail changes in a cohort of psoriasis patients.
  • To identify factors associated with the occurrence of nail abnormalities in psoriasis.
  • To explore the correlation between nail changes and disease severity, duration, patient demographics, and joint involvement.

Main Methods:

  • A cross-sectional study involving 410 patients diagnosed with psoriasis.

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  • Interviews and clinical examinations were conducted to assess nail status.
  • Data analysis included calculating prevalence rates and identifying correlations with clinical parameters.

    • Main Results:

    • The overall prevalence of nail changes was 78.0% in the studied population.
    • The most frequent nail changes observed were pitting (67.5%) and onycholysis (67.2%).
    • Nail abnormalities were significantly more common in patients with moderate to severe psoriasis, longer disease duration (>5 years), older age (>50 years), and those with scalp, periungual psoriasis, or joint involvement.

    Conclusions:

    • Nail changes are highly prevalent in psoriasis patients and manifest in various forms.
    • Disease severity, chronicity, patient age, and associated joint involvement are significant risk factors for nail changes in psoriasis.
    • These findings underscore the importance of evaluating nail status in all psoriasis patients for optimal treatment strategies.