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Published on: May 6, 2018
Uncommon cause of fever in a child with steroid-dependent nephrotic syndrome
Sidharth Kumar Sethi1, Shyam Bansal1, Ronith Chakraborty2
1Kidney Institute, Medanta, The Medicity Hospital, Gurgaon, Haryana, India, and.
Background:
Children with nephrotic syndrome are vulnerable to developing infections due to a state of relative immunodeficiency, malnourishment, and use of immunosuppression. Case characteristics: We herein report the case of a 3-year-old child with steroid-dependent nephrotic syndrome who presented to us with fever of unknown origin.
Observation:
The child was found to have an atypical mixed infection with mycoplasma and cytomegalovirus.
Outcome:
The infection completely resolved with appropriate treatment and lowering of immunosuppression. Message: Persistently febrile pediatric patients, especially in the setting of recent immunosuppression and absence of otherwise-identified infectious pathogens, should be screened for atypical mixed infections.
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