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Acetylation phenotypes in patients with bladder carcinoma
M P Bicho1, L Breitenfeld, A A Carvalho
1Instituto de Química Fisiológica, Faculdade de Medicina, Lisboa, Portugal.
Annales De Genetique
|January 1, 1988
Abstract:
The present study was done to evaluate the possible association of bladder carcinoma with the slow acetylator phenotype in a portuguese population. 49 patients with bladder carcinoma were compared to a normal control group of 84 individuals. No statistically significant association was detected. But when subdividing the group of slow acetylators it is found that in the subgroup with 12-36% acetylation there is a higher percentage of patients, which is statistically significant. These results are in agreement with two other studies, using populations of similar ethnic origin.