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Updated: Dec 15, 2025

Network Pharmacology Prediction and Experimental Validation of Trichosanthes-Fritillaria thunbergii Action Mechanism Against Lung Adenocarcinoma
Published on: March 3, 2023
Immune system activation by natural products and complex fractions: a network pharmacology approach in cancer
Alejandra Gomez-Cadena1,2,3, Alfonso Barreto3, Susana Fioretino3
1Department of Pathology and Immunology, Targeting of Cytokine Secreting Lymphocyte group, Geneva University, Geneva, Switzerland.
Abstract:
Natural products and traditional herbal medicine are an important source of alternative bioactive compounds but very few plant-based preparations have been scientifically evaluated and validated for their potential as medical treatments. However, a promising field in the current therapies based on plant-derived compounds is the study of their immunomodulation properties and their capacity to activate the immune system to fight against multifactorial diseases like cancer. In this review we discuss how network pharmacology could help to characterize and validate natural single molecules or more complex preparations as promising cancer therapies based on their multitarget capacities.
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