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Discovery of New Intracellular Pathogens by Amoebal Coculture and Amoebal Enrichment Approaches
Published on: October 27, 2013
First report of a new corneal pathogen: Phaeoacremonium parasiticum
Horace Massa1, Arnaud Riat2, Georgios D Panos3
1Department of Ophthalmology, Geneva University Hospitals, Rue Alcide - Jentzer 22, 1211, Genève 14, CH, Switzerland. Horace.massa@hcuge.ch.
Abstract:
Keratitis is a public health issue in developing countries and a potentially sight-threatening condition. Collagen fibrils in the corneal stroma are parallels to each other. Fundamental substance maintains the same space between collagen fibrils. That is how corneal transparency can be achieved. Any damage which can modify this structure will lead to corneal opacity and loss of vision. Fungal keratitis might appear in up to one-third of cases. Nevertheless, fungal keratitis remains poorly described and understood. Herein, we present the first ever reported case of corneal infection due to Phaeoacremonium parasiticum in a young patient. We describe the clinical and microbial characteristics, and we also discuss the use of confocal microscopy in early diagnosis of this infection.
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