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Updated: Dec 15, 2025
A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Evaluation on the separated effect of 13 hemoglobin variants by a new automatic Hba1c analyzer
Rui Li1, Huamei Tang1, Lijuan Kan1
1Medical Laboratory of Shenzhen Luohu People's Hospital, Shenzhen, China.
Objective:
To evaluate the effect of a new type of automatic glycated hemoglobin analyzer on the separation of abnormal hemoglobin.
Methods:
Samples diagnosed as hemoglobin variants by capillary electrophoresis and gene testing were selected, and HbA1c analyzer was used for separation and detection.
Results:
A total of 13 hemoglobin variants in 40 samples could be separated from the normal peaks.
Conclusions:
The variant mode of hemoglobin HbA1c can identify a variety of hemoglobin variants, and the type of variants can be preliminarily determined according to the retention time and characteristic peak shape of the variants.
