Related Experiment Video
Updated: Dec 15, 2025

Rescue of Recombinant Newcastle Disease Virus from cDNA
Published on: October 11, 2013
Emerging of a novel natural recombinant fowl adenovirus in China
Lu Lv1,2, Hao Lu2,3,4,5, Kai Wang1
1Shanghai Veterinary Research Institute, The Chinese Academy of Agricultural Sciences, Shanghai, China.
Abstract:
Outbreaks of hydropericardium syndrome and inclusion body hepatitis caused by fowl adenovirus (FAdV) have occurred in China since June 2015, resulting in significant economic loss to poultry industry. In this study, a novel FAdV, designated as AH720, with recombination among serotype FAdV-8a and FAdV-8b was isolated and characterized in China. Full genome analysis revealed that the AH720 has the genome backbone from FAdV-8b and the fibre gene from FAdV-8a. In an infection study, although AH720 was not lethal to chickens, AH720 did cause characteristic lesions of inclusion body hepatitis in the infected chickens. All these data not only provide strong evidences for the recombination among different serotype FAdVs, but also highlight the necessary for monitoring the molecular epidemiology of such recombinant FAdV to develop efficient strategies against FAdV.
More Related Videos
07:15Preparation of Pseudo-Typed H5 Avian Influenza Viruses with Calcium Phosphate Transfection Method and Measurement of Antibody Neutralizing Activity
Published on: November 22, 2021
06:57In Vitro Culture for H5N1-Specific Duck T Cells and Detection of Immune Responses Using Intracellular Cytokine Staining Method
Published on: May 30, 2025
Related Concept Videos
Viral Recombination
Viral Mutations