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Author Spotlight: Advancing Antiviral Strategies Through Novel Immunocapture and Mass Spectrometry Techniques

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A Surface Coating that Rapidly Inactivates SARS-CoV-2.

Saeed Behzadinasab¹, Alex Chin², Mohsen Hosseini¹

¹Department of Chemical Engineering and Center for Soft Matter and Biological Physics, Virginia Tech, Blacksburg, Virgina 24061, United States.

ACS Applied Materials & Interfaces

|July 14, 2020

Summary

A new cuprous oxide (Cu2O) and polyurethane coating significantly reduces SARS-CoV-2 virus viability on surfaces. This antiviral coating offers enhanced protection against the virus that causes COVID-19 on everyday objects.

Keywords:

COVID-19 Cu2O SARS-CoV-2 coating coronavirus cuprous oxide virucidal

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Determining Viral Disinfection Efficacy of Hot Water Laundering

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Published on: June 21, 2022

Area of Science:

Materials Science
Virology
Public Health

Background:

SARS-CoV-2, the virus responsible for COVID-19, can persist on solid surfaces for up to a week, posing an infection risk.
Contaminated surfaces represent a significant transmission route for the virus, necessitating strategies to mitigate surface viability.

Purpose of the Study:

To develop and evaluate a novel coating designed to decrease the longevity of SARS-CoV-2 on solid materials.
To assess the efficacy and durability of a cuprous oxide (Cu2O)-based coating for antiviral applications.

Main Methods:

Fabrication of a coating comprising cuprous oxide (Cu2O) particles integrated with polyurethane.
Testing the coating's ability to reduce viral titer on glass and stainless steel surfaces after a 1-hour exposure.
Evaluating coating adhesion, durability through cross-hatch testing, and performance after prolonged water immersion and disinfection cycles.

Main Results:

The Cu2O-polyurethane coating reduced SARS-CoV-2 viral titer by approximately 99.9% on coated glass and stainless steel within 1 hour compared to uncoated surfaces.
The coating demonstrated excellent adhesion to various materials, including glass, stainless steel, doorknobs, pens, and credit card keypads.
The coating maintained its integrity and antiviral activity after 13 days of water immersion and repeated exposure/disinfection cycles.

Conclusions:

The developed Cu2O-polyurethane coating is a highly effective antiviral surface treatment against SARS-CoV-2.
Its durability and adherence to common materials suggest potential for widespread application on frequently touched objects to reduce disease transmission.
This innovation offers a promising approach to enhance public health safety by minimizing surface-based viral spread.