Related Experiment Video
Updated: Dec 15, 2025

Semi-Automated Analysis of Peak Amplitude and Latency for Auditory Brainstem Response Waveforms Using R
Published on: December 9, 2022
Cepstral Peak Prominence Values for Clinical Voice Evaluation
Olivia Murton1,2, Robert Hillman1,2,3,4, Daryush Mehta1,2,3,4
1Speech and Hearing Bioscience and Technology, Division of Medical Sciences, Harvard Medical School, Boston, MA.
Cepstral Peak Prominence (CPP) values were identified to distinguish voice disorders with high accuracy. These CPP values can aid clinicians in evaluating voice quality and dysphonia severity.
Area of Science:
- Speech and Hearing Sciences
- Acoustic Analysis
- Clinical Voice Assessment
Background:
- Cepstral Peak Prominence (CPP) is a quantitative measure used in voice analysis.
- Establishing normative CPP values is crucial for reliable clinical voice evaluation.
- Previous research has explored CPP, but specific cutoffs for distinguishing voice disorders and correlating with perceptual ratings require further definition.
Purpose of the Study:
- To identify specific Cepstral Peak Prominence (CPP) values using common analysis tools (ADSV and Praat) that can differentiate between speakers with and without voice disorders.
- To explore the potential of CPP values in estimating auditory-perceptual ratings of overall dysphonia severity.
Main Methods:
- Cepstral Peak Prominence (CPP) was computed using the Analysis of Dysphonia in Speech and Voice (ADSV) program and Praat.
- Experiment 1 involved 295 patients with voice disorders and 50 healthy controls producing sustained /a/ vowels and the Rainbow Passage.
- Experiment 2 analyzed recordings from 32 speakers with varying dysphonia severity, correlating CPP with listener ratings using linear regression.
Main Results:
- CPP cutoff values were identified to distinguish between disordered and healthy voices with up to 94.5% accuracy for sustained /a/ vowels and the Rainbow Passage.
- Specific cutoffs were 11.46 dB (ADSV) and 14.45 dB (Praat) for sustained /a/, and 6.11 dB (ADSV) and 9.33 dB (Praat) for the Rainbow Passage.
- CPP values demonstrated a correlation with auditory-perceptual ratings of dysphonia severity, with an R-squared value up to .74 in Experiment 2.
Conclusions:
- The identified CPP cutoff values serve as normative references for clinical voice evaluation using sustained /a/ vowels and the Rainbow Passage.
- These CPP values can assist clinicians in identifying the presence of voice disorders.
- The study provides a preliminary framework for using CPP to predict perceived dysphonia severity, aiding in objective voice assessment.
Related Concept Videos
Physical Assessment of the Respiratory Tract III: Percussion
Percussion in Respiratory Assessment
Percussion evaluates underlying tissue composition with audible and tactile vibrations,...
Physical Assessment of the Respiratory Tract IV: Auscultation
Breath Sounds
Breath sounds are categorized into vesicular, bronchovesicular, and bronchial.
Physical Assessment of the Respiratory Tract II: Palpation
Thoracic Palpation
Thoracic palpation detects tenderness, masses, lesions, respiratory excursions, and vocal fremitus. The nurse assesses...
Assessment of Ventilation II: Respiratory Depth and Rhythm
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
Respiratory System Abnormal Finding II: Palpation and Auscultation
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
Assessment of Airway, Skin Color, and Use of Accessory Muscles
Introduction
The initial evaluation of a patient's respiratory system...

