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Related Experiment Video

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Personality and HbA1c: Findings from six samples.

Yannick Stephan1, Angelina R Sutin2, Martina Luchetti2

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Higher conscientiousness, a personality trait, is linked to lower haemoglobin A1c (HbA1c) levels and reduced diabetes risk. This finding suggests conscientiousness may aid in identifying individuals at risk for diabetes.

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Area of Science:

  • Psychology
  • Endocrinology
  • Public Health

Background:

  • Personality traits are linked to health outcomes, including diabetes risk.
  • Previous research often relied on self-reported diabetes diagnoses, not objective glycemic markers.
  • The association between specific personality domains and objective glycemic control requires further investigation.

Purpose of the Study:

  • To examine the relationship between the Big Five personality traits and haemoglobin A1c (HbA1c) levels.
  • To determine if personality traits are associated with the risk of undiagnosed diabetes.
  • To explore potential mediating roles of body mass index (BMI) and physical activity.

Main Methods:

  • Analysis of personality data and HbA1c levels from over 26,000 individuals aged 16-104.
  • Inclusion of participants from diverse community samples in the US, Europe, and Japan.
  • Statistical examination of associations, including meta-analysis and mediation analysis considering BMI and physical activity.

Main Results:

  • Higher conscientiousness was consistently associated with lower HbA1c levels across samples.
  • Conscientiousness demonstrated a significant association with a reduced risk of elevated HbA1c (≥6.5%).
  • Body mass index and physical activity partially mediated the link between conscientiousness and HbA1c; other traits showed no consistent associations.

Conclusions:

  • Conscientiousness is replicably associated with better glycemic control (HbA1c) in adults.
  • Assessing conscientiousness may enhance the identification of individuals at risk for diabetes.
  • Personalized interventions targeting conscientiousness could potentially aid in regulating HbA1c levels.