One year in review 2020: systemic sclerosis.

Area of Science:

• Rheumatology
• Immunology
• Dermatology

Background:

• Systemic sclerosis (SSc) is a severe autoimmune connective tissue disease.
• It involves microangiopathy, immune dysregulation, and widespread fibrosis.
• SSc presents with heterogeneous manifestations and variable prognosis.

Purpose of the Study:

• To provide an overview of significant literature contributions on Systemic sclerosis published last year.
• To aid clinicians in understanding and managing SSc patients.
• To highlight recent insights into SSc pathogenesis, organ involvement, and treatment.

Main Methods:

• Literature review of significant contributions from the past year.
• Synthesis of novel insights into SSc pathogenesis.
• Compilation of updated information on organ involvement and treatment.

Main Results:

• Recent literature offers novel insights into SSc pathogenesis.
• New findings address specific organ involvement in SSc.
• Updated treatment strategies and management approaches are discussed.

Conclusions:

• Regularly reviewing recent literature is crucial for effective SSc management.
• Understanding novel insights improves patient care and prognosis.
• This overview assists clinicians in staying current with SSc advancements.