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Related Experiment Videos

Tranquilizer use before and after coronary bypass operation.

L D Young1, J J Barboriak, A J Anderson

  • 1Department of Psychiatry, Medical College of Wisconsin, Milwaukee 53226.

Journal of Psychosomatic Research
|January 1, 1988
PubMed
Summary

Tranquilizer use decreased after coronary bypass surgery (CABG). Pre- and post-surgery factors like neuroticism, heart attack, and angina influenced tranquilizer use, with angina relief being key.

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Area of Science:

  • Cardiology
  • Psychosomatic Medicine
  • Pharmacology

Background:

  • Tranquilizer use is prevalent in patients with coronary heart disease.
  • Previous research linked tranquilizer use to various cardiac conditions and patient factors.

Purpose of the Study:

  • To investigate biological, psychological, and social factors associated with tranquilizer use in male patients before and after coronary bypass surgery (CABG).
  • To determine the impact of CABG on tranquilizer consumption.

Main Methods:

  • A questionnaire assessed 1046 male patients' variables pre- and post-coronary bypass surgery.
  • Tranquilizer use was correlated with biological, psychological (neuroticism), and social factors.
  • Univariate and multivariate analyses were employed.

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Main Results:

  • Coronary bypass surgery led to a reduction in tranquilizer use.
  • Pre-surgery tranquilizer use correlated with neuroticism, myocardial infarction, and cardiac/analgesic medication use.
  • Post-surgery, angina pectoris emerged as an additional factor associated with tranquilizer use.

Conclusions:

  • Cardiac disease variables, beyond coronary atherosclerosis, significantly influence tranquilizer use in patients undergoing evaluation.
  • Neurotic traits play a secondary role in tranquilizer use.
  • Relief of angina pectoris is crucial for reducing tranquilizer use, and its persistence post-surgery warrants attention.