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Sub-group, Sub-type, and Cell-type Heterogeneity of Ependymoma
Stephen C Mack1, Kelsey C Bertrand1
1Baylor College of Medicine, Texas Children's Cancer and Hematology Centers, Dan L. Duncan Cancer Center, Houston, TX 77030, USA.
Cancer Cell
|July 15, 2020
Abstract:
Ependymomas are aggressive central nervous system tumors that resist chemotherapy. In this issue of Cancer Cell, Gojo et al. dissect the single cell transcriptional landscapes of ependymoma to define cellular programs that mediate therapeutic resistance, tumor aggressiveness, and potential targets for therapy.
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