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Related Experiment Video

Updated: Dec 14, 2025

The Role of Anatomical Dissection in Defining Colic and Small Bowel Artery Lymphovascular Bundles in the D3 Volume of Small and Large Bowel Mesentery
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Neck Dissection for Cervical Lymph Node Metastases from Remote Primary Malignancies.

Shogo Shinohara1, Hiroyuki Harada2, Masahiro Kikuchi3

  • 1Department of Head and Neck Surgery, Kobe City Medical Center General Hospital, Minatojima-Minamimachi 2-1-1, Chuo-ku, Kobe 650-0047, Japan.

Medicina (Kaunas, Lithuania)
|July 16, 2020
PubMed
Summary

Neck dissection can improve survival for patients with cervical lymph node metastases from remote cancers. Fewer positive nodes after surgery correlate with better overall survival rates, highlighting the procedure's effectiveness.

Keywords:
FDG/PET-CThead and neck metastasisneck dissectionremote primarysurvival analysis.

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Nuclear Medicine

Background:

  • Cervical lymph node metastases from remote primary tumors indicate advanced cancer with poor prognosis.
  • Advancements in non-surgical cancer management increase options for surgical debulking, potentially improving survival.
  • Neck dissection is a viable definitive therapy for select patients with resectable cervical metastases.

Purpose of the Study:

  • To assess the effectiveness of neck dissection for cervical lymph node metastases originating from remote primary malignancies.
  • To evaluate patient survival rates following neck dissection with curative intent.

Main Methods:

  • Retrospective review of 18 patients (2010-2019) undergoing neck dissection for remote cervical metastases.
  • Analysis of patient demographics, clinical characteristics, and survival outcomes.
  • Evaluation of fluorodeoxyglucose positron emission tomography-computed tomography (FDG-PET/CT) accuracy for lymph node localization.

Main Results:

  • Primary tumor sites included lung, breast, thymus, esophagus, stomach, cervix, ovary, and testis.
  • FDG-PET/CT identified positive nodes in 17/18 patients (19 levels), while pathological examination revealed 28 positive levels out of 50 dissected.
  • The three-year overall survival rate was 70%, with significantly higher survival (81%) in patients with 0-1 positive nodes compared to those with >2 positive nodes (51%).

Conclusions:

  • Neck dissection for cervical lymph node metastases from remote primary cancers may enhance patient prognoses.
  • Improved outcomes are noted, especially when combined with advancements in anticancer agents and radiotherapy.
  • The number of positive lymph nodes post-dissection is a critical prognostic factor.