Ocular findings in patients with attention deficit and hyperactivity

P B Ulucan Atas1, O M Ceylan2, Y E Dönmez3

  • 1Department of Ophtalmology, Elazig Fethi Sekin City Hospital, Elazig, Turkey. pamuk.b@hotmail.com.

Insights

Children with attention-deficit/hyperactivity disorder (ADHD) exhibit reduced contrast sensitivity and thinner nasal retinal nerve fiber layer (RNFL) thickness. These findings suggest potential visual processing differences in ADHD and may inform environmental adjustments.

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Pediatrics

Background:

  • Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder.
  • Ocular characteristics in children with ADHD are not fully understood.
  • Previous research has not extensively explored visual functions like contrast sensitivity and retinal structure in ADHD.

Purpose of the Study:

  • To investigate ocular findings, contrast sensitivity, color perception, and macular and retinal nerve fiber layer (RNFL) thickness in children with ADHD.
  • To compare these visual parameters between children with ADHD and healthy controls.

Main Methods:

  • A prospective study involving 37 children aged 6-16 diagnosed with combined ADHD and 37 age-matched healthy controls.
  • Ophthalmological examinations including Ishihara color vision testing and Functional Acuity Contrast Test.
  • Spectral-domain optical coherence tomography (SD-OCT) for macular and RNFL thickness measurements.

Main Results:

  • No significant differences in ocular findings, color vision, or convergence insufficiency were observed.
  • Children with ADHD showed significantly lower contrast sensitivity at four spatial frequencies (1.5, 3, 12, 18 cpd).
  • The ADHD group had significantly thinner nasal quadrant RNFL and macular thickness compared to controls.

Conclusions:

  • Children with ADHD demonstrate significantly reduced contrast sensitivity and thinner nasal RNFL thickness.
  • These visual alterations may be associated with ADHD pathophysiology.
  • Recommendations include enhancing contrast in daily tools and environments for individuals with ADHD.
Abstract

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