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Vitamin D and COVID-19.

George Trovas1, Symeon Tournis2

  • 1Laboratory for Research of the Musculoskeletal System, "Th. Garofalidis" Medical School, National and Kapodistrian University of Athens, 10 Athinas Str., 14561, Athens, Greece. trovas1@otenet.gr.

Hormones (Athens, Greece)
|July 16, 2020
PubMed
Summary
This summary is machine-generated.

Vitamin D deficiency may increase COVID-19 complications. While research is ongoing, doctors should treat vitamin D deficiency regardless of its link to respiratory infections.

Keywords:
Bone and muscle healthCOVID-19Clinical trialsVitamin D

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Area of Science:

  • Public Health
  • Infectious Diseases
  • Nutritional Science

Background:

  • Observational studies suggest a correlation between high rates of vitamin D deficiency (hypovitaminosis D) and increased COVID-19 severity.
  • These findings stem from epidemiological data, indicating potential links between low vitamin D levels and adverse outcomes in COVID-19 patients.

Purpose of the Study:

  • To examine the potential association between vitamin D status and COVID-19 outcomes.
  • To inform clinical practice regarding vitamin D supplementation in the context of the pandemic.

Main Methods:

  • Review of epidemiological data and observational studies.
  • Analysis of reported correlations between hypovitaminosis D prevalence and COVID-19 mortality/complications.

Main Results:

  • Epidemiological data indicate a potential link between vitamin D deficiency and increased susceptibility to severe COVID-19 outcomes.
  • Limitations of current data include reliance on observational studies, precluding definitive causal conclusions.

Conclusions:

  • While awaiting more definitive research, clinical management should prioritize treating vitamin D deficiency.
  • Vitamin D status should be addressed in patients, irrespective of its direct association with respiratory infections like COVID-19.