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Related Concept Videos

Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

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Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
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Endocarditis I: Introduction01:25

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Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
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Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

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Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
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Bacterial Signaling01:30

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Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
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Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
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Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

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Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
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Bacteraemia after leadless pacemaker implantation.

Christophe Garweg1,2, Bert Vandenberk1, Sander Jentjens3

  • 1Department of Cardiology, University Hospitals Leuven, Leuven, Belgium.

Journal of Cardiovascular Electrophysiology
|July 16, 2020
PubMed
Summary
This summary is machine-generated.

Infections from transvenous pacemakers are serious. This study found no leadless pacemaker endocarditis in patients with bloodstream infections, suggesting leadless devices may offer better protection against cardiac device infections.

Keywords:
18F-FDG PET/CTbacteraemiainfectionleadless pacemaker

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Area of Science:

  • Cardiology
  • Infectious Diseases
  • Medical Devices

Background:

  • Transvenous pacemaker infections cause significant morbidity and mortality.
  • Leadless pacemakers, with smaller surface areas, may reduce bacterial seeding during bloodstream infections.
  • This study investigates the incidence and outcomes of bacteremia in patients with Micra leadless pacemakers.

Purpose of the Study:

  • To determine the incidence and outcomes of bacteremia in patients implanted with Micra leadless pacemakers.
  • To assess the potential for leadless pacemakers to resist bacterial seeding during bloodstream infections.
  • To report findings from 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) in a subgroup of patients.

Main Methods:

  • Retrospective cohort study of 155 patients who received a Micra TPS implant.
  • Identification of patients who developed bacteremia, confirmed by at least two positive blood cultures.
  • Review of clinical outcomes and 18F-FDG PET/CT findings in a subset of patients.

Main Results:

  • 15 out of 155 patients (9.7%) developed bacteremia at a median of 226 days post-implant.
  • Gram-positive bacteria were the most common cause (73.3%).
  • No leadless pacemaker endocarditis was observed; 18F-FDG PET/CT scans showed no signs of infection around the device.

Conclusions:

  • In this cohort, bacteremia in patients with Micra leadless pacemakers did not result in leadless pacemaker endocarditis.
  • Leadless pacemakers may be more resistant to infection compared to transvenous systems.
  • Further research is warranted to confirm these findings in larger populations.