Related Experiment Video

Updated: Dec 14, 2025

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
14:09

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance

Published on: March 21, 2013

21.5K

Risk Factors for Orthostatic Hypertension in Children

Yang Hu1, Bing He2, Zhenhui Han3

  • 1Department of Pediatrics, Peking University First Hospital, Beijing, China; Research Unit of Clinical Diagnosis and Treatment of Pediatric Syncope and Cardiovascular Diseases, Chinese Academy of Medical Sciences, Beijing, China.

The Journal of Pediatrics
|July 16, 2020
PubMed

Insights

Pediatric orthostatic hypertension is linked to higher body mass index and red blood cell distribution width, alongside lower water intake and sleep duration. Addressing these factors may reduce the risk in children.

Area of Science:

  • Pediatric cardiology and internal medicine.
  • Clinical research on cardiovascular health in children.

Background:

  • Orthostatic hypertension (OH) is a condition characterized by a significant drop in blood pressure upon standing.
  • Identifying risk factors for pediatric OH is crucial for early intervention and management.

Purpose of the Study:

  • To investigate the risk factors associated with orthostatic hypertension in children.
  • To determine the relationship between lifestyle factors, anthropometric measurements, and the incidence of pediatric OH.

Main Methods:

  • A case-control study involving 80 children diagnosed with orthostatic hypertension and 51 healthy children.
  • Data collection included demographic information, clinical history, daily water intake, sleep duration, standing test results, and complete blood count.
  • Logistic regression analysis was employed to identify independent risk factors for pediatric orthostatic hypertension.

Main Results:

  • Children with orthostatic hypertension exhibited higher body mass index (BMI) and red blood cell distribution width (RDW) compared to controls.
  • Lower daily water intake and shorter sleep duration were observed in the orthostatic hypertension group.
  • Logistic regression revealed that overweight, obesity, daily water intake <800 mL, and increased RDW were significant risk factors for pediatric OH. Increased sleep duration showed a protective effect.

Conclusions:

  • Elevated body mass index (overweight and obesity), insufficient daily water intake, and increased red blood cell distribution width are significant risk factors for pediatric orthostatic hypertension.
  • Inadequate sleep duration is also identified as a contributing factor to the development of orthostatic hypertension in children.
  • These findings highlight the importance of lifestyle modifications, including maintaining adequate hydration and sleep, and managing weight, in preventing pediatric orthostatic hypertension.
Abstract

Keywords:
orthostatic hypertensionorthostatic intolerancepediatricsred blood cell distribution widthrisk factor

More Related Videos

Software for Analysis of Heart Rate and Blood Pressure Time-series Data from the Valsalva Maneuver14:28

Software for Analysis of Heart Rate and Blood Pressure Time-series Data from the Valsalva Maneuver

Published on: June 27, 2025

762
Measuring Cardiac Autonomic Nervous System ANS Activity in Children09:45

Measuring Cardiac Autonomic Nervous System ANS Activity in Children

Published on: April 29, 2013

21.3K

Related Concept Videos

Alterations in Blood Pressure01:30

Alterations in Blood Pressure

Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
1.7K
Factors affecting Blood pressure01:28

Factors affecting Blood pressure

Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:
6.1K
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
3.5K
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
584
Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
540
Special considerations while measuring blood pressure01:28

Special considerations while measuring blood pressure

When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
1.0K