[Psychopharmacologic studies on the combined effect of alcohol and oxazepam on reactivity pattern. II. Subjective...

Psychopharmacological investigations of the subjective state of being and the reactivity pattern of a group of 14 probands show a good agreement with the alterations of performance reported in the first part of this publication and with the data on polarity profiles. In addition to a sedative effect the interaction of alcohol and oxazepam in the oxazepam trial results in dysphoric changes of mood and related significant alterations of polarity profiles. A correlation of the changes of performance and the alterations of the polarity profiles with the respective blood levels of alcohol and oxazepam could be demonstrated.