[Immunohistochemical study of alpha-1-antichymotrypsin and GFAP in glioma]

GFAP is a specific antigen of glial element, but Alpha-1-antichymotrypsin has not been reported in the literature Alpha-1-antichymotrypsin was guided by GFAP using PAP method to the astrocytes of 137 gliomas. 120 (87%) gliomas were positive for Alpha-1-antichymotrypsin. Of these 120 gliomas, 86 (72%) gave diffuse distribution, 17 (14%) gave focal distribution, and 17 (14%) gave scattered distributions. Alpha-1-antichymotrypsin in glioma tissue may be an important tumor marker for diagnosis.