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Related Concept Videos

Infection01:20

Infection

11.4K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
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Related Experiment Video

Updated: Dec 14, 2025

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
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Human strongyloidiasis: identifying knowledge gaps, with emphasis on environmental control.

Michael J Taylor1, Tara A Garrard1, Francis J O'Donahoo1

  • 1Health and Environment, School of the Environment, Flinders University, Adelaide, SA, Australia.

Research and Reports in Tropical Medicine
|July 17, 2020
PubMed
Summary

Environmental control of the parasitic worm Strongyloides is hindered by knowledge gaps. Understanding its prevalence and complex life cycle is crucial for developing effective, non-clinical interventions against strongyloidiasis.

Keywords:
Strongyloides stercoralisenvironmental controlnematodeparasitologystrongyloidiasis

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Area of Science:

  • Parasitology
  • Environmental Health
  • Infectious Diseases

Background:

  • Strongyloides is a poorly understood human parasitic nematode.
  • Current estimates suggest 100-370 million infections globally, with over 300 million likely due to diagnostic and mapping inaccuracies.
  • Strongyloidiasis is a neglected tropical disease, with limited research outside clinical settings.

Purpose of the Study:

  • Identify literature gaps hindering environmental control of Strongyloides.
  • Highlight limitations in current research for developing environmental interventions.
  • Explore potential environmental control strategies beyond clinical treatment.

Main Methods:

  • Literature review focusing on environmental control challenges.
  • Analysis of Strongyloides prevalence, distribution, and life cycle complexities.
  • Examination of factors contributing to its spread in specific regions, like Australia.

Main Results:

  • Prevalence and distribution of Strongyloides remain unclear, extending beyond tropical/subtropical zones.
  • The complex life cycle prevents in-vitro culturing, limiting laboratory research for environmental control.
  • Environmental control measures (e.g., soil alteration) are overlooked due to reliance on antihelminthic drugs.

Conclusions:

  • Environmental control of Strongyloides is underdeveloped and urgently needed.
  • Further research into the parasite's environmental factors and life cycle is vital.
  • Relying solely on antihelminthics may be unsustainable; environmental interventions are critical for long-term control.