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Related Concept Videos

Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

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Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
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Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

128
Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
128
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

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Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
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Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

300
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
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Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

278
The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
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Cardiac Lymphoma Presenting with Recurrent STEMI.

Munis Raza1, Sohail Ikram1, Nina Williams1

  • 1UNIVERSITY OF LOUISVILLE, LOUISVILLE, KENTUCKY.

Methodist Debakey Cardiovascular Journal
|July 17, 2020
PubMed
Summary

Metastatic cardiac lymphoma, though rare, can mimic heart attacks. This case highlights a fatal presentation of lymphoma infiltrating the heart, leading to myocardial infarction and ventricular rupture.

Keywords:
ST-segment elevationcardiac lymphomacardiogenic shockcoronary artery diseaseleft ventricular free wall rupture

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Area of Science:

  • Cardiology
  • Oncology
  • Pathology

Background:

  • Primary cardiac tumors are rare; secondary cardiac tumors are more common.
  • Cardiac involvement occurs in about 18% of non-Hodgkin's lymphoma cases at autopsy.
  • Clinical signs of cardiac lymphoma are often subtle and detected late.

Observation:

  • Clinical signs of cardiac lymphoma are often subtle and missed until late stages.
  • A rare case of metastatic cardiac lymphoma presented as ST-segment elevation myocardial infarction.

Findings:

  • The lymphoma caused transmural myocardial necrosis.
  • This led to left ventricular free wall rupture and cardiogenic shock.

Implications:

  • This case underscores the importance of considering metastatic cardiac lymphoma in patients with lymphoma and myocardial infarction symptoms.
  • Early recognition and diagnosis are crucial for managing this rare but severe condition.