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Updated: Dec 14, 2025

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
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Published on: June 28, 2018

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A Rare Case of Ventilator-Associated Pneumonia Caused by Cupriavidus Pauculus

Syed A Huda1, Sanjay Yadava1, Sara Kahlown2

  • 1Internal Medicine, State University of New York (SUNY) Upstate Medical University, Syracuse, USA.

Cureus
|July 17, 2020
PubMed

Insights

Ventilator-associated pneumonia (VAP) is a serious hospital infection. This case highlights successful treatment of VAP caused by Cupriavidus pauculus, an uncommon bacterium, using cefepime.

Area of Science:

  • Infectious Diseases
  • Critical Care Medicine
  • Microbiology

Background:

  • Ventilator-associated pneumonia (VAP) is a common intensive care unit (ICU) infection.
  • It leads to increased patient morbidity and mortality.
  • Typical causes include common gram-negative rods and gram-positive cocci.

Observation:

  • A case of VAP caused by Cupriavidus (C.) pauculus is presented.
  • C. pauculus is a less commonly identified bacterium in VAP cases.
  • The patient was intubated and in the ICU.

Findings:

  • Successful treatment of VAP caused by C. pauculus was achieved.
  • Intravenous cefepime was the chosen therapeutic agent.
  • This demonstrates cefepime's efficacy against this specific pathogen.

Implications:

  • Highlights the importance of identifying uncommon pathogens in VAP.
  • Suggests cefepime as a potential treatment option for C. pauculus VAP.
  • Contributes to understanding VAP etiology and management strategies.
Keywords:
cupriavidus pauculusicuintubatedvap

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