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Updated: Dec 14, 2025

Listeria monocytogenes Infection of the Brain
Published on: October 2, 2018
Postpartum listeria meningitis
Claudia Colomba1, Raffaella Rubino1, Antonio Anastasia1
1Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Italy.
Abstract:
Listeria monocytogenes is a small Gram positive, intracellular bacillus known to cause a foodborne disease in immunocompromised patients and other high-risk groups. The infection that usually is asymptomatic or resembles a mild influenza like disease, in some risk groups can cause meningitis and brain abscesses. In pregnant women, L. monocytogenes may lead to abortion or delivery of an acutely ill infant. We describe a case of L. monocytogenes meningitis occurred in a young puerpera without immunological disorders or other risk factors. We think that because the puerperium is accompanied by the same physiological changes in immune response that features pregnancy, a higher infectious risk should be considered during this period of woman's life. Therefore, an empiric antimicrobial therapy also for listeriosis should be promptly started in meningitis that arises in post-partum period so to achieve the best outcome of the infection.
Insights
Listeria monocytogenes can cause meningitis in healthy postpartum women. Prompt antimicrobial therapy is crucial for better outcomes during this high-risk period.
Area of Science:
- Microbiology
- Infectious Diseases
- Obstetrics & Gynecology
Background:
- Listeria monocytogenes is a Gram-positive bacterium causing foodborne illness, primarily in immunocompromised individuals.
- Infections can range from mild flu-like symptoms to severe conditions like meningitis and brain abscesses.
- Pregnant women are at higher risk, potentially leading to adverse pregnancy outcomes.

