[MODERN INSUES OF ESSENTIAL TRACE ELEMENTS LEVEL INFLUENCE ON CHILDREN AND ADULTH HEALTH (REVIEW)]

Area of Science:

• Neuroscience
• Pediatrics
• Biochemistry

Background:

• Essential trace elements, Copper and Zinc, are vital for neurodevelopmental processes.
• Disbalances in blood concentrations (deficiency or excess) of these microelements are observed in children and adolescents.
• Previous research suggests a correlation between trace element levels and cognitive symptoms.

Purpose of the Study:

• To review the role of essential trace elements, Copper and Zinc, in neurodevelopment.
• To explore the association between Copper and Zinc levels and symptoms of inattention, hyperactivity, and impulsivity in children and adolescents.
• To examine the relationship between trace elements and cognitive symptomatology.

Main Methods:

• Systematic review of existing literature.
• Analysis of studies focusing on children and adolescents aged 3-16 years.
• Evaluation of data on blood concentrations of Copper and Zinc and their correlation with neurodevelopmental symptoms.

Main Results:

• Copper and Zinc play significant roles in neurodevelopmental processes.
• Deficiency and high concentration disbalances of Copper and Zinc are associated with inattention, hyperactivity, and impulsivity symptoms.
• Clinical symptoms are significantly associated with trace element levels and positively correlated with cognitive symptomatology.

Conclusions:

• Copper and Zinc are critical for neurodevelopment in children and adolescents.
• Altered levels of these trace elements are linked to behavioral and cognitive issues.
• Understanding the functional connectivity and impact of trace elements is a key challenge in pediatric clinical practice.