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Development of "Advancing People of Color in Clinical Trials Now!": Web-Based Randomized Controlled Trial Protocol.
Alicia Chung1, Azizi Seixas1, Natasha Williams1
1NYU Grossman School of Medicine, New York, NY, United States.
A culturally tailored website, Advancing People of Color in Clinical Trials Now! (ACT Now!), aims to boost clinical trial participation. This intervention increased literacy, self-efficacy, and willingness to enroll among people of color.
Area of Science:
- Health equity
- Clinical trial recruitment
- Health disparities
Background:
- Participation in clinical trials by people of color is significantly lower than that of white subjects.
- The "Advancing People of Color in Clinical Trials Now!" (ACT Now!) initiative developed a culturally tailored website to address this disparity.
- The ACT Now! website is designed to influence decision-making processes regarding clinical trial enrollment among diverse populations.
Purpose of the Study:
- To evaluate the effectiveness of a culturally tailored website in enhancing clinical trial literacy.
- To assess the impact of the website on participants' self-efficacy in making clinical trial decisions.
- To determine if the website increases the willingness of people of color to enroll in clinical trials.
Main Methods:
- A cluster randomized trial involving 100 participants (50 in the intervention group, 50 in the control group).
- The intervention group accessed the culturally tailored ACT Now! website, while the control group used a standard recruitment website.
- Measurements of clinical trial literacy and enrollment willingness were taken at baseline, 1-month post-intervention, and 3-month follow-up.
Main Results:
- The ACT Now! initiative developed a culturally tailored website to improve clinical trial literacy, self-efficacy, and enrollment willingness among racial and ethnic groups.
- A community-based participatory research approach, utilizing a community steering committee (CSC), was employed to build trust and gather input.
- The study enrolled 100 participants, with data analysis expected by June 2020 and results publication in fall 2020.
Conclusions:
- The ACT Now! website demonstrates potential to address the underrepresentation of people of color in clinical trials.
- This accessible web-based intervention can help bridge the gap in clinical trial enrollment for minority populations.
- Culturally tailored resources are crucial for improving engagement and participation in clinical research among diverse communities.
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