Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rates, Timing, and Predictors of Retreatment Across Risk-Cohorts in Retinopathy of Prematurity: Intravitreal Bevacizumab Injection vs Laser.

American journal of ophthalmology·2026
Same author

Genetic Testing in Inherited Retinal Disease: Current Strategies and Future Directions.

Journal of personalized medicine·2026
Same author

Trends in the Initial Treatment for Retinopathy of Prematurity in the United States.

Ophthalmic surgery, lasers & imaging retina·2026
Same author

Influence of Anti-VEGF Injections on Longitudinal Changes in Vascular Metrics Measured by OCTA in Age Related Macular Degeneration: A Retrospective Real-World Study.

Clinical ophthalmology (Auckland, N.Z.)·2026
Same author

Bilateral Opposing Lens Dislocation and Retinal Detachment in LTBP2-Associated Weill-Marchesani Syndrome: Surgical Sequencing and Multidisciplinary Pediatric Management.

Retinal cases & brief reports·2026
Same author

Minimizing Risk in Scleral Buckle Surgery: A Novel Approach to Belt Loop Creation Using a Guarded Diamond Blade.

Retinal cases & brief reports·2026

Related Experiment Video

Updated: Dec 14, 2025

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats
04:16

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

Published on: March 7, 2025

843

Rhegmatogenous Retinal Detachment after Intravitreal Injection.

Karen R Brown1, Nicolas A Yannuzzi1, William E Smiddy1

  • 1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.

Ophthalmology. Retina
|July 17, 2020
PubMed
Summary

Rhegmatogenous retinal detachment (RRD) after intravitreal injections is rare but can occur. While surgical outcomes are often favorable, visual acuity may be limited by the severity of the detachment and underlying macular disease.

Keywords:
Intravitreal injectionRhegmatogenous retinal detachment

More Related Videos

An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach
07:13

An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach

Published on: December 7, 2016

13.7K
Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate
05:58

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate

Published on: September 11, 2013

21.3K

Related Experiment Videos

Last Updated: Dec 14, 2025

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats
04:16

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

Published on: March 7, 2025

843
An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach
07:13

An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach

Published on: December 7, 2016

13.7K
Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate
05:58

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate

Published on: September 11, 2013

21.3K

Area of Science:

  • Ophthalmology
  • Retinal Surgery
  • Pharmacology

Background:

  • Intravitreal injections are common treatments for macular diseases.
  • Rhegmatogenous retinal detachment (RRD) is a potential, though rare, complication following these injections.
  • Understanding the risk factors and outcomes of RRD post-injection is crucial for patient management.

Purpose of the Study:

  • To investigate the clinical characteristics of patients who develop RRD after intravitreal pharmacologic injections.
  • To evaluate the surgical outcomes and visual acuity recovery in this patient cohort.

Main Methods:

  • A retrospective case series design was employed.
  • Identified patients diagnosed with RRD within three months of receiving an intravitreal injection for macular disease.
  • Collected data on surgical repair, visual acuity (VA), and retinal reattachment rates.

Main Results:

  • Thirteen patients with RRD post-intravitreal injection were identified.
  • The average time from injection to RRD diagnosis was 27 days.
  • Retinal reattachment was successful in 92% of cases, but only 23% regained baseline visual acuity.

Conclusions:

  • RRD following intravitreal injection is uncommon, but may be associated with prior retinal surgery or other risk factors.
  • Surgical success for retinal reattachment is generally high.
  • Visual outcomes are often compromised by macula-off detachments and pre-existing macular pathology.