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Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ

Kan Saito1, Frederic Michon2, Aya Yamada1

  • 1Division of Pediatric Dentistry, Department of Oral Health and Development Sciences, Tohoku University Graduate School of Dentistry, Sendai 980-8575, Japan.

Iscience
|July 17, 2020
PubMed
Summary

The transcription factor Sox21 is crucial for tooth development, preventing enamel hypoplasia and hair formation. Its disruption leads to ectopic hair growth and impaired enamel, highlighting its role in cell fate determination.

Keywords:
Developmental GeneticsRodent DentistryTranscriptomics

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