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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Maternal mortality and COVID-19.

Maira L S Takemoto1, Mariane O Menezes1, Carla B Andreucci2

  • 1Medical School of Botucatu, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|July 18, 2020
PubMed
Summary
This summary is machine-generated.

This study analyzed 20 COVID-19 maternal deaths in Brazil, finding most deaths occurred postpartum and often involved comorbidities like asthma. These findings highlight disparities compared to global data.

Keywords:
COVID-19coronavirusmaternal mortalitypostpartum periodpregnancysevere acute respiratory syndrome coronavirus 2

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Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Public Health

Background:

  • The COVID-19 pandemic has had a significant impact on maternal health globally.
  • Understanding the specific burden of COVID-19-related maternal mortality in Brazil is crucial for targeted interventions.

Purpose of the Study:

  • To provide a comprehensive overview of COVID-19-related maternal deaths in Brazil.
  • To compare Brazilian maternal mortality data with international reports.

Main Methods:

  • Systematic search of data from the Brazilian Ministry of Health, State Departments of Health, and media coverage.
  • Data collection included timing of death (pregnancy/postpartum), gestational age, mode of birth, maternal age, comorbidities, and location of death.
  • Analysis of 20 identified COVID-19-related maternal deaths.

Main Results:

  • Twenty maternal deaths attributed to COVID-19 were identified, with ages ranging from 20 to 43 years.
  • Most deaths (16/20) occurred postpartum, and 11 cases had at least one comorbidity, with asthma being the most frequent.
  • Deaths were concentrated in the Northeast and Southeast regions, with São Paulo being a significant epicenter.

Conclusions:

  • This represents the largest series of COVID-19 maternal deaths reported to date.
  • Healthcare access barriers, varied pandemic control measures, and prevalent risk factors may contribute to Brazil's observed maternal mortality outcomes.
  • Findings underscore the need for tailored strategies to mitigate COVID-19's impact on maternal health in Brazil.