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Related Concept Videos

Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

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Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
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Acute Pyelonephritis II: Diagnostic Studies and Management01:28

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Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
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Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
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Related Experiment Video

Updated: Dec 14, 2025

Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis
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[An abscessed granulomatous prostatitis].

K Chevalier1, J Ferreira1, D Cabral2

  • 1Service de Médecine Interne, Hôpital Ambroise Paré, Université Paris Saclay, 9 Avenue Charles de Gaulle, 92100 Boulogne-Billancourt, France.

La Revue De Medecine Interne
|July 18, 2020
PubMed
Summary
This summary is machine-generated.

Granulomatosis with polyangiitis can present as non-infectious granulomatous prostatitis. Early diagnosis and treatment with steroids and rituximab are crucial for managing systemic involvement.

Keywords:
Abcès prostatiqueGranulomatose avec polyangéiteGranulomatosis with polyangiitisProstatic abscessProstatiteProstatitis

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Area of Science:

  • Urology
  • Rheumatology
  • Pathology

Background:

  • Prostatic abscesses typically indicate bacterial prostatitis.
  • Granulomatous prostatitis is an uncommon cause of prostatic abscesses.
  • Systemic inflammatory conditions can manifest in the prostate.

Observation:

  • A 55-year-old male presented with acute urinary retention and sterile urine despite leukocyturia.
  • Imaging revealed a prostatic abscess and a lung nodule.
  • Prostate and lung biopsies showed granulomas without infection.

Findings:

  • The patient was diagnosed with granulomatosis with polyangiitis (GPA) based on characteristic granulomas and elevated anti-proteinase 3 antibodies.
  • Treatment with corticosteroids and rituximab led to clinical improvement and reduced inflammatory markers.
  • GPA should be considered in cases of non-infectious granulomatous prostatitis with systemic symptoms.

Implications:

  • This case highlights the importance of considering systemic vasculitis in the differential diagnosis of prostatic abscesses.
  • Prompt recognition and immunosuppressive therapy can prevent severe complications of GPA.
  • Multidisciplinary management involving urologists, rheumatologists, and pathologists is essential for optimal patient outcomes.