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Updated: Dec 14, 2025

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
Published on: August 11, 2008
Detection of Mycobacterium Tuberculosis DNA in Buccal Swab Samples from Children in Lima, Peru
Juan A Flores1,2, Roger Calderón3,4, Annelies W Mesman5
1From the Escuela de Tecnología Médica, Universidad Privada San Juan Bautista, Lima, Peru.
Abstract:
We examined Mycobacterium tuberculosis DNA detection from buccal swab samples collected from children in Lima, Peru. DNA was extracted and amplified via real-time polymerase chain reaction. Sensitivity was 21% (95% confidence interval [CI]: 7%-42%) in 24 culture-confirmed tuberculosis cases and 4.6% (95% CI: 1%-13%) in 65 clinically diagnosed unconfirmed cases. Sensitivity was highest for smear-positive tuberculosis. Specificity was 99% in the 199 controls (95% CI: 96%-100%).
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